First, let me give you a nice listOriginally Posted by Bubba
Quake 4
Doom 3
Unreal Tournament 2004
Unreal Tournament 2003
Quake 3
Unreal Tournament
Quake 2
Tribes 2
That's just out of one genre of games that have Linux ports, Never Winter Nights also had a native Linux port. I know most of the titles I mentioned are from 2 major developers (id Software and Epic Games) but you will notice they make a killing just off licensing the engine, which includes Linux for those companies that want it.
Also, you will find that even FPS games that strictly have a Windows client will have a Linux server binary available due to a large number of hosting providers using it for hosting.
Don't forget about Mac OS either, the move to Intel I think might just give it a good kick into the gaming market. Blizzard has been targeting the Mac OS platform for years.
Oh, and should I even mention the reported use of OpenGL by the PlayStaion3?
Small Edit: forgot to mention, how many CAD/Modeling programs use Direct3D for rendering? Its an OpenGL world there, has been for a long time.
Oh, and since when has DirectSound been low level? Its an abstraction layer, just like SDL/OpenAL.