If the OP doesn't even know what arguments to use, probably not.
Too little information. Can you provide a code snippet?
So you have something like this:
i am having trouble setting up a function to sum one of the columns of a two column array. especially what arguments i'm meant to use.
and you have to add all the numbers in array or array? Well, your prototype could look something like this:
int add_col(int array, int size_of_array);
/* function call */
printf("%i\n", add_col(array, 100));