I'm hoping that Apple implements a Wine-like program right into the core of Mac OS X -- similar to Rosetta, except that it wouldn't be emulating. What makes this so possible is that Apple has (or had) access to Windows source code, so they would be able to make a Wine-like application with much greater compatilbility.
The Wine developers are currently reverse-engineering the Windows API, so development goes much slower and compatiblity is harder to come by.